Generic Prednisolone 40 mg


Prednisolone is used to treat a variety of ailments, including inflammation (swelling), severe allergies, adrenal problems, arthritis, asthma, blood or bone marrow problems, endocrine problems, eye or vision problems, stomach or bowel problems, lupus, skin conditions, kidney problems, ulcerative colitis, and multiple sclerosis flare-ups.

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Generic Prednisolone 40 mg

Manufacturer Various
Shipping time 6-14 days
Active Ingredient Prednisolone
Manufacturer Macleods
Type steroids, corticosteroids are a type of anti-inflammatory drug
Buy other strengths Prednisolone 5 mg, Prednisolone 10 mg, Prednisolone 20 mg, Prednisolone 40 mg

Prednisolone 40 mg, the active ingredient in Prednisolone, is a member of the corticosteroid drug class. It is used to treat inflammatory and auto-immune conditions like allergies, including severe allergic reactions, inflammation of the lungs, asthma, blood vessels, the heart, the bowel and kidneys, the muscles and joints, including rheumatoid arthritis, the eye and nervous system, the skin, infections, and cancers (such as leukemia, lymphoma, and myeloma).

Prednisolone 40 mg is also used to enhance steroid levels when the body cannot create natural steroids on its own and to avoid organ rejection following transplantation. It is also used to treat high calcium levels in the affected people, typically characterized by symptoms including nausea, cramping in the stomach, pain in the bones, and muscle weakening.

Patients with fungal infections or recently received live vaccines are not advised to use Prednisolone 40 mg. If you have an infection, hypothyroidism, fits, myasthenia gravis (muscle weakness), diabetes, high blood pressure, heart failure, liver disease, or renal illness, let your doctor know before using WYSOLONE 10MG.

Use of WYSOLONE 10MG during pregnancy and when nursing should be avoided. Also used with caution in teens and youngsters (below 18 years of age). Before using the medication, speak with your doctor. Infection, symptoms of low potassium levels (such as constipation and rapid heartbeat), symptoms of increased blood and urine sugar levels (such as increased thirst and frequent urination), high blood pressure, thinner skin, and impaired wound healing are the most frequent side effects of taking Prednisolone 40 mg. Before using the medication, speak with your doctor.

USES OF Prednisolone 40 mg

  • To treat inflammatory and auto-immune conditions such as:
    • Allergies (including severe allergic reactions)
    • Inflammation (affecting lungs including asthma, blood vessels & heart, bowel and kidney, muscles and joints including rheumatoid arthritis, eye/nervous system)
    • Skin conditions, infections, and cancers (such as leukemia, lymphoma, and myeloma)
  • To prevent organ rejection after transplantation
  • To boost steroid levels when the body cannot make enough natural steroids on its own.
  • To treat high calcium levels in the body.

HOW WYSOLONE PREDNISOLONE WORKS

Prednisolone works by blocking the production of polymorphonuclear leukocytes (immune cells responsible for inflammation and allergic reactions), preventing inflammatory and allergic reactions in the affected individuals, thus treating the conditions.

DIRECTIONS FOR USE

Take Prednisolone 40 mg as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of Wysolone prednisolone depending upon your age, body weight and disease conditions.

SIDE EFFECTS OF Prednisolone 40 mg

COMMON

  • Infections such as tuberculosis
  • Lower concentration of certain hormones, Cushing’s-like appearance, growth retardation in children
  • Signs of low levels of potassium such as constipation, fast heartbeat, fatigue, muscle damage, muscle weakness, or spasms
  • Signs of high sodium levels such as confusion, muscle twitching, seizures, coma
  • Signs of increased sugar in the blood and urine such as increased thirst, frequent urination, excessive hunger
  • Osteoporosis (weak and brittle bones)
  • Swelling due to fluid accumulation
  • High blood pressure
  • Thinner skin
  • Impaired wound healing
  • Muscle wasting

UNCOMMON

  • Mental disorders (at high doses)
  • Cataracts, glaucoma (increased eye pressure with pain)

RARE

  • Depression
  • Mania in patients without a history of psychiatric illness
  • Increased benign pressure in the skull
  • Breakdown of bone tissue
  • Tendon rupture

Stop taking Wysolone 20 and contact your doctor immediately if you experience any of the following side effects:

  • Signs of a severe allergic reaction (including angioedema) such as swelling of the face, tongue, or throat, difficulty swallowing, hives and difficulty breathing, fever, drop in blood pressure
  • Signs of pheochromocytoma crisis (rare, life-threatening adrenal gland tumor) such as anxiety, headache, palpitations, sweating, pale skin
  • Signs of acute renal and kidney crisis (due to scleroderma) such as high blood pressure and decreased urine output
  • Suicidal thoughts
  • Exposure to people infected with chickenpox, shingles, and measles

WARNING & PRECAUTIONS

PREGNANCY

Wysolone Prednisolone 20 mg should be used with caution in pregnant women and in women planning for pregnancy. Consult your doctor before taking Prednisolone 20 mg.

BREASTFEEDING

Prednisolone 20 mg 10MG should be used cautiously in breastfeeding women since the medicine may pass through milk. Consult your doctor before taking Prednisolone 20 mg.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you experience visual disturbance, dizziness or tiredness while taking Wysolone 20. Consult your doctor before taking this medicine.

KIDNEY

Prednisolone 40 mg should be used with caution in patients with kidney failure. Consult your doctor about taking medicine.

LIVER

Prednisolone 40 mg should be used with caution in patients with liver disease. Consult your doctor before taking Wysolone.

ALLERGY

Do not take Wysolone 20 if you are allergic to Prednisolone or any other ingredient in this medicine.

HEART DISEASE

Wysolone should be used with caution in patients with heart disease such as heart failure. Consult your doctor before taking medicine.

OTHERS

Prednisolone is not recommended for use if you:

  • Have fungal infection
  • Recently had any live vaccinations

Before taking Wysolone, inform your doctor if you have:

  • Or get an infection
  • An underactive thyroid gland (hypothyroidism)
  • Or had seizures
  • Myasthenia gravis (muscle weakness)
  • Or had been treated for tuberculosis
  • Gastric, duodenal ulcer, or inflammatory bowel disease such as ulcerative colitis, diverticulitis
  • Diabetes
  • High blood pressure
  • Or had blood clots such as vein thrombosis
  • Mood swings or psychotic tendencies
  • Osteoporosis
  • An adrenal tumor (pheochromocytoma)
  • Surgically created new blood vessels or intestinal connections
  • Scleroderma (a rare auto-immune disease characterized by chronic hardening and tightening of the skin)
  • Intolerance to certain sugars, such as lactose

Use in pediatrics:

Wysolone should be used with caution in children and adolescents (below 18 years of age). Consult your doctor before taking it.

Use in geriatrics:

Wysolone should be cautioned in elderly patients (above 65 years of age). Consult your doctor before taking it.

INTERACTIONS

Drug interactions:

  • Rifampicin, isoniazid (medicines used to treat tuberculosis)
  • Blood thinners like warfarin
  • Carbamazepine, phenobarbital, phenytoin (medicines used to treat epilepsy)
  • Anticholinergics (drugs used to treat Parkinson’s disease or asthma) Ex. trihexyphenidyl, benztropine, ipratropium, tiotropium.
  • Cholinesterase inhibitors (medications used to treat myasthenia gravis or Alzheimer’s disease) Ex. neostigmine, edrophonium
  • Insulin (a medicine used to treat diabetes)
  • Anti-diabetic drugs (medicines used to treat diabetes) Ex. metformin, glipizide
  • Cobicistat (a medicine used to treat HIV infection)
  • Estrogens (birth control pill used to prevent pregnancy)
  • Acetylsalicylic acid and other non-steroidal anti-inflammatory medicines (used to treat pain and inflammation) Ex. paracetamol, ibuprofen
  • Potassium lowering diuretics (medicines used to treat high blood pressure) such as thiazides (Ex. chlorothiazide, chlorthalidone), furosemide
  • Medicines used to treat asthma such as xanthines (Ex. theophylline), beta-2 stimulants (Ex. salbutamol, terbutaline, salmeterol, formoterol)
  • Amphotericin B (medicines used to treat fungal infection)

Overdosage:

If you or anyone else accidentally take too much of Wysolone, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

Drug : Prednisolone
Pharmacological Category : Corticosteroids
Therapeutic Indication : Inflammatory & Auto-immune conditions, Organ rejection (after transplantation), Hypercalcemia
Dosage Forms : Tablet, Dispersible Tablet, Eye Drops, Ophthalmic Suspension, Oral Drops, Solution, Suspension, Syrup

MORE INFORMATION

  • Keep Prednisolone 40 mg out of reach of children
  • Do not store Prednisolone 40 mg above 25°C

FAQs ABOUT Prednisolone 40 mg

What are the uses of Prednisolone 40 mg?

Prednisolone 40 mg treats inflammatory and auto-immune conditions such as allergies, inflammation (affecting lungs, blood vessels & heart, bowel, kidneys, muscles, joints, eye or nervous system), skin conditions, infections and cancers (such as leukemia, lymphoma, and myeloma). It is also used to prevent organ rejection after transplantation, which is also indicated to boost steroid levels. It is also used to treat hypercalcemia, generally characterized by symptoms such as stomach pain, nausea, bone pain, and muscle weakness.

How does Prednisolone 40 mg work?

Prednisolone 40 mg works by blocking the production of polymorphonuclear leukocytes (immune cells responsible for inflammation and allergic reactions), which prevents the occurrence of inflammatory and allergic reactions in the affected individuals treating inflammatory and auto-immune conditions.

What side are effects seen with the use of Prednisolone 40 mg?

The most common side effects seen associated with the use of WYSOLONE are infections, signs of low potassium levels (such as constipation, fast heartbeat), signs of increased sugar in the blood and urine (such as increased thirst, frequent urination), high blood pressure, thinner skin, and impaired wound healing. Consult your doctor before taking medicine.

Can Prednisolone 40 mg be used in a pregnant and breastfeeding woman?

Prednisolone 40 mg should be used cautiously during pregnancy and by women planning for pregnancy. It should also be used cautiously in breastfeeding women as the medicine may pass through milk. Consult your doctor before taking the medication.

Can Prednisolone 40 mg be given to children?

Prednisolone 40 mg should be used cautiously in children and adolescents (below 18 years). Long-term usage should be avoided. Your doctor will decide the dose, frequency and duration depending on the child’s age, body weight, and disease conditions.

REFERENCES

1. KD. Tripathi. Corticosteroids. Essentials of medical pharmacology. Eighth 8th edition. 2013. Page – 313.

2. Yana Puckett; Aishah Gabbar; Abdullah A. Bokhari. Prednisone. NIH National Library of Medicine, National center for biotechnology information. StatePearls. May 2022. [Accessed on 9th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK534809/

3. Ciro Manzo, Jordi Serra-Mestres, Alberto Castagna, and Marco Isetta. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. August 2018. [Accessed on 9th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163472/

4. Accord UK Ltd. Electronic Medicines Compendium (EMC). [Revised on March 2021] [Accessed 9th July 2022] https://www.medicines.org.uk/emc/files/pil.5887.pdf

5. Healing Pharma India Pvt. Ltd. Predniheal 40. [Accessed on 9th July 2022] https://www.healingpharma.in/product/predniheal-40/

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