Susten 8% Gel 1.35gm (Progesterone) 10 Tubes


Price/Tube: $12.9
Composition: Progesterone (Natural Micronized) (8% w/w)
Manufacturer: Sun Pharmaceutical Industries Ltd
Storage: Store below 30°C

$129.00

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Introduction

Susten, 8% Gel, is used to restore menstrual cycles in women who have stopped menstruating. It is a female hormone that plays a critical role in the regulation of ovulation (the release of an egg from a woman’s ovary) and menstruation. It is used to aid in the treatment of infertility.

Susten, 8% Gel, should be used as directed by your physician. Do not exceed or decrease the recommended dosage, and do not use it for an extended period. You may be asked to continue taking this medication for an extended period following confirmation of pregnancy.

This medication may cause vaginal bleeding, vaginal discharge, and itching. Notify your doctor if any of these symptoms persist or worsen. Occasionally, individuals experience a severe allergic reaction that necessitates immediate medical attention.

It may not be appropriate for everyone, and you should inform your physician if you have or have had breast cancer, unusual vaginal bleeding, or liver disease. If you have liver, kidney, heart problems or diabetes, or asthma, you may be monitored more closely. To be safe, inform your doctor of your medical history. Inform your doctor of all other medications that may interact with or be affected by this medication. You will almost certainly undergo several tests both before and during treatment to determine the health of your womb. It is generally recommended that you avoid using any other vaginal products or cream while taking this medication.

Uses of Susten Vaginal gel

Benefits of Susten Vaginal gel

Hormone Replacement Therapy (HRT) is a medication used to treat menopausal symptoms such as hot flushes, night sweats, mood swings, vaginal dryness, and decreased sexual drive. Because menopause can last several years, this treatment can significantly improve your daily life and mood. Progesterone is one of two critical hormones used in this treatment (the other is estrogen). While vaginal tablets and gels are convenient to administer hormones, they may not alleviate all symptoms. You should take this medication exactly as prescribed by your doctor and for the entire duration of the prescription.

Infertility in females

Susten, 8% Gel, contains progesterone, a female hormone necessary for ovulation and menstruation regulation. It is used to induce menstruation in women who have not reached menopause but are experiencing irregular periods due to a deficiency of natural progesterone in the body. Progesterone aids in the preparation of the uterus for pregnancy by thickening the uterine lining (endometrium). This significantly increases the likelihood of a successful pregnancy. To ensure that the medication is effective, you must take it exactly as prescribed. You may be asked to continue with this treatment for an extended period following conception.

Side effects of Susten Vaginal gel

The majority of side effects are mild and resolve as your body adjusts to the medication. Consult your physician if they persist or cause you concern.

SERIOUS

  • allergic skin reactions

COMMON

  • headache
  • feeling tired
  • stomach or gut cramps
  • breast tenderness

How to use Susten Vaginal gel

This medication is only for external use. Use it according to your doctor’s dosage and duration recommendations. Before using, check the label for directions. Apply the gel to the affected area after cleaning and drying it. After applying, thoroughly wash your hands.

How Susten Vaginal gel works

Sustain 8% Gel is a progesterone analog (female hormone). It aids in the establishment and maintenance of pregnancy. Additionally, it inhibits the thickening of the endometrium (uterine lining) caused by estrogen.

WARNING & PRECAUTIONS

PREGNANCY

  • SUSTEN 8% is generally contraindicated during pregnancy. If, however, this medication assists you in becoming pregnant, you may be asked to continue taking it to support your new pregnancy.

BREASTFEEDING

  • SUSTEN 8% should be used cautiously if you are a breastfeeding mother. Consult your physician before using this medication.

DRIVING AND APPLICATION OF MACHINES

  • Avoid driving or operating machinery while taking this medication, as it may cause dizziness.

ALCOHOL

  • Avoid alcohol consumption while taking this medication, as it may increase your risk of experiencing side effects.

KIDNEY

  • SUSTEN 8% should be used cautiously in patients who have kidney disease. Consult your physician for guidance.

LIVER

  • SUSTEN 8% should be used cautiously in patients who have liver disease. Consult your physician for guidance.

ALLERGY

  • Take this medication with caution if you are allergic to progesterone.

LUNGS

  • Patients with asthma or other respiratory disorders should use SUSTEN 8% with caution. Consult your physician for guidance.

DISEASE OF THE HEART

  • SUSTEN 8% should be used cautiously in patients with heart disease. Consult your physician for guidance.

OTHERS

Avoid using this medication if you are:

have unexplained vaginal bleeding, porphyria (an inherited blood disorder), breast or genital organ cancer, or are at risk for breast or genital organ cancer, have had a previous abortion, or have had a blood clot due to thrombophlebitis (swollen veins), thromboembolic disorder (a blocked blood vessel), or a stroke.

INTERACTIONS

Inform your doctor about all medications you take, including over-the-counter and prescription medications, as well as herbal supplements.

Quick Tips

  • Susten 8% Gel assists in increasing your chances of becoming pregnant by replacing low progesterone levels during the luteal phase. It prepares the uterine lining for the reception and nourishment of a fertilized egg.
  • Susten, 8% Gel, may be continued for an additional 10 to 12 weeks if you become pregnant or until your progesterone levels reach an acceptable level.
  • Additionally, it aids in regulating the menstrual cycle in women who are unable to have a regular period due to a deficiency of the hormone progesterone.
  • Each applicator should be used only once to insert the gel into your vagina and then discarded.
  • It exposes your body to significantly less hormone than progesterone pills or injections, avoiding various gastric side effects.
  • Tampons or other vaginal products should be avoided for at least six hours before and six hours after using Susten 8 percent Gel.
  • During this period, you may experience a brownish or white discharge that may cause irritation, pain, or swelling of the vagina. This is not uncommon, but if it bothers you, consult your physician.

FAQ’s about Susten Progesterone Gel

What does progesterone gel do?

  • Intravaginal progesterone gel is used to supplement or replace progesterone in infertile women undergoing assisted reproductive technology treatment (ART). Additionally, intravaginal progesterone gel is used to treat secondary amenorrhea (absence of menses).

Why is progesterone gel used in pregnancy?

  • Progesterone, a naturally occurring hormone that can also be applied as a vaginal gel, has been shown to reduce preterm birth rate in women with a short cervix, which is a risk factor for these types of deliveries.

How do you apply progesterone gel?

  • While sitting or lying on your back with your knees bent, gently insert the applicator into the vagina.

When should I use progesterone gel?

  • This medication is used to aid in the pregnancy of women who are undergoing an Assisted Reproductive Technology (ART) treatment program. Additionally, it is used in the treatment of secondary amenorrhea. This occurs when a woman’s menstrual cycle is interrupted due to low progesterone levels.

References

Tripathi, KD. Estrogens, Progestins, and Contraceptives are all hormones and related drugs. Medical pharmacology fundamentals. The seventh edition was published in 2013. Pages 316-319.

2. Levin, Ellis R., and Hammes, Stephen R. Progestins and Estrogens The Pharmacological Foundations of Therapeutics, Goodman & Gilman. The Twelfth Edition McGraw Hill Medical, New York, 2011. 1180-1184.

3. Women’s and Children’s Hospital at Brigham and Women’s Hospital. Comparison of Crinone 8% Intravaginal Gel and Intramuscular Progesterone Supplementation in Women Under the Age of 40 Years for In Vitro Fertilization (IVF) and Embryo Transfer (ET) Cycles. NIH ClinicalTrials.gov, National Library of Medicine, United States of America. [September 2011] [Accessed November 7th, 2020] https://clinicaltrials.gov/ct2/show/NCT00656201

4. Merck KGaA. Phase 3 Trial to Assess the Efficacy and Safety of COL-1620 Vaginal Progesterone Gel. National Institutes of Health. National Library of Medicine of the United States of America ClinicalTrials.gov. [Updated December 2015] [Accessed November 7th, 2020] https://clinicaltrials.gov/ct2/show/NCT01863680

5. Osamu Ishihara, Shoji Kokeguchi, Naoki Hayashi, Daniela Rogoff, Shin Shimizu, and Shoji Kokeguchi. In a phase III trial, 8% vaginal progesterone gel was used to support the luteal phase in Japanese women undergoing in vitro fertilization or fresh embryo transfer cycles. NIH National Institutes of Health, National Library of Medicine, United States of America. [January 2017] [Accessed November 7th, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715867/

Electronic Medicines Compendium, Central Pharma (Contract Packaging) Ltd. (EMC). [Augmented in August 2019] [Accessed November 7th, 2020] https://www.medicines.org.uk/emc/files/pil.1283.pdf

7. Central Pharma (Contract Packaging) Ltd. (HPRA). [January 2016] [Accessed November 7th, 2020] % 208 % https://www.hpra.ie/img/uploaded/swedocuments/235-1-PIL-CRINONE 20W-W% 20PROGESTERONE% 20VAGINAL% 20GEL% 20(15)% 20(CZECH)% 20 (MAR percent 2015) -2171633-05012016143145-635876011067688750.pdf

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