Testosterone Injections

Why is this medicine prescribed?

Testosterone cypionate (Depo-Testosterone), testosterone enanthate (Xyosted, obtainable generically), testosterone undecanoate (Aveed), and testosterone pellet (Testopel) are forms of testosterone injection used to treat symptoms of low testosterone in men who have hypogonadism (a condition by which the body does not produce enough natural testosterone). Testosterone is used only for men with low testosterone levels caused by certain medical conditions, including disorders of the testicles, pituitary gland (a small gland within the brain), or hypothalamus (part of the brain) that cause hypogonadism. Your doctor will order certain lab tests to check your testosterone levels to see if they are low before you begin to use testosterone injection. Testosterone enanthate (available generically) and testosterone pellet (Testopel) are also used to stimulate puberty in males with delayed puberty. Testosterone enanthate (available generically) injection could also be used in certain women with a type of breast most cancers called mammary cancer that has spread to other parts of the body. Testosterone should not be used to treat the signs of low testosterone in men who have low testosterone due to aging (‘age-related hypogonadism’). Testosterone is in a class of medications called androgenic hormones. Testosterone is a hormone produced by the body that contributes to the expansion, development, and functioning of the male sexual organs and typical male characteristics. Testosterone injection works by supplying synthetic testosterone to replace the testosterone that’s normally produced naturally in the body. When used to treat breast cancer, testosterone works by stopping the release of estrogen.

How should testosterone injections be used?

Testosterone cypionate, testosterone enanthate (available generically), and testosterone undecanoate injection come as a solution (liquid) to be injected right into a muscle and as a pellet to be injected underneath the skin by a doctor or nurse in an workplace setting or clinic. Testosterone enanthate injection (Xyosted) comes as a solution (liquid) to be injected subcutaneously (under the skin) once every week by yourself or a caregiver.

Testosterone injection may management your symptoms but will not cure your condition. Your doctor may adjust your dose of testosterone depending on the amount of testosterone in your blood during your treatment and your reaction to the medication.

Always take a look at your testosterone enanthate (Xyosted) resolution before you inject it. It should be clear to light yellow in color and free of visible particles. Do not use it if it is cloudy, incorporates visible particles, or if the expiration date on the package has passed.

You can inject testosterone enanthate injection (Xyosted) within the left or right side of your stomach (abdomen) except your navel and the area 2 inches around it. Do not inject into an area where the skin is tender, bruised, red, or hard or the place you have scars, tattoos, or stretch marks.

Your healthcare provider will show you how to use testosterone enanthate injection (Xyosted). Be sure that you simply understand these directions, and ask your healthcare provider if you have any questions.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

Other uses use of testosterone injections

This medication may be prescribed for other uses; ask your doctor or pharmacist for more info.

What special precautions should I follow?

Before receiving testosterone injection,

  • inform your doctor and pharmacist if you are allergic to testosterone, another drug, or any of the ingredients in testosterone injection products. Ask your pharmacist for a list of the ingredients.
  • inform your doctor and pharmacist what prescription and nonprescription medications, nutritional vitamins, nutritional supplements, and herbal merchandise you are taking or plan to take. Be positive to mention the medicines listed in the IMPORTANT WARNING section and any of the following: anticoagulants (blood thinners) such as warfarin (Coumadin, Jantoven); insulin (Apidra, Humalog, Humulin, others); drugs for diabetes; and oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos). Your physician may need to change the doses of your medications or monitor you carefully for side effects.
  • in case you are male, tell your doctor if you have breast cancer or have or may have prostate cancer. Also tell your doctor if you have heart, liver, or kidney disease. Your doctor may tell you that you shouldn’t receive a testosterone injection.
  • inform your doctor if you have or have ever had sleep apnea (breathing stops for short periods of time during sleep); benign prostate hyperplasia (BPH; an enlarged prostate); high blood levels of calcium; cancer; diabetes; depression or other mental illness; or lung disease.
  • you should know that some testosterone products should not be used in women (Aveed, Xyosted). Otherwise, women should not receive this medication if they are or may become pregnant or are breastfeeding. Testosterone may harm the baby.
  • you must know that there have been reports of serious side effects in individuals who use testosterone at higher doses, along with other male sex hormone products, or in ways other than directed by a physician. These side effects may include a heart attack, heart failure, or other heart problems; stroke and mini-stroke; liver disease; seizures; or mental health changes such as depression, mania (frenzied, abnormally excited mood), aggressive or unfriendly behavior, hallucinations (seeing things or hearing voices that do not exist), or delusions (having strange thoughts or beliefs that have no basis in reality). People who use higher doses of testosterone than beneficial by a doctor may also experience withdrawal signs such as depression, extreme tiredness, craving, irritability, restlessness, loss of appetite, inability to fall asleep or stay asleep, or a decreased sex drive, if they all of a sudden stop using testosterone. Be sure to make use of testosterone injection exactly as directed by your doctor.

What particular dietary directions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What side effects can this medicine cause?

Testosterone injection may trigger side effects. Tell your doctor if any of these signs are severe or do not go away:

  • acne
  • breast enlargement or pain
  • hoarseness
  • deepening of voice
  • pain, redness, bruising, bleeding, or hardness at injection site
  • tiredness
  • difficulty falling asleep or staying asleep
  • mood swings
  • weight gain
  • headache
  • joint pain
  • back pain

Some unwanted effects can be serious. If you expertise any of these symptoms or those listed in the IMPORTANT WARNING part, call your doctor instantly:

  • lower leg pain, swelling, warmth, or redness
  • nausea or vomiting
  • swelling of the hands, feet, ankles, or lower legs
  • difficulty respiration, especially during sleep
  • erections that happen too often or that last too long
  • difficulty urinating, weak urine flow, frequent urination, sudden need to urinate right away, blood in the urine
  • yellowing of the skin or eyes
  • pain within the upper right part of the stomach
  • mood changes including depression, anxiety, or becoming suicidal (thinking about harming or killing oneself or planning or making an attempt to do so)

Testosterone injection may cause a decrease in the number of sperm (male reproductive cells) produced, especially if it is used at high doses. Talk to your doctor about the risks of using this medication in case you are a man and would like to have children.

Testo may increase the danger of developing prostate cancer. Talk to your doctor about the risks of receiving this medication.

Testo injection may cause the bones to mature more rapidly than normal in children who receive the medication. This means that the children may stop growing sooner than expected and may have a shorter than expected adult height.

Testo injection may cause other unwanted effects. Call your doctor if you have any unusual problems while receiving this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about the storage and disposal of this medication?

Keep testosterone enanthate injection (Xyosted) in the container it came in, tightly closed, and out of reach of kids. Store it at room temperature and away from light, excess heat, and moisture (not in the bathroom). Do not refrigerate or freeze.

It is essential to keep all medication out of sight and reach of kids as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young youngsters can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the treatment in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other individuals cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to get rid of your medicine is through a medicine take-back program. Talk to your pharmacist or contact your local rubbish/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also out there online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, instantly call emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your physician may order sure tests to check your body’s response to testo injection.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are receiving testosterone injection.

Do not let anybody else use your testosterone enanthate injection (Xyosted). Testo is a controlled substance. Prescriptions may be refilled only a limited variety of times; ask your pharmacist if you have any questions.

It is important so that you can keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or different dietary supplements. You should deliver this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important data to carry with you in case of emergencies.

Brand names

  • Aveed®
  • Delatestryl®
  • Depo-Testosterone®
  • Testopel®
  • Xyosted®

Other names

  • testosterone cypionate
  • testosterone enanthate
  • testosterone undecanoate
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